Shiota, Y., Fujita, I., Hayashi, S., Ohtsuki, S. and Kondo, T. Integrated transcriptomic, proteomic, and pharmacologic profiling of 2D and 3D patient-derived GCTB cell lines reveals culture-dependent drug response determinants. Proteomics, e70136 (2026). DOI:10.1002/pmic.70136.
Fujita, I., Kimura, A. and Yamashita, A. A force balance model for a cell size-dependent meiotic nuclear oscillation in fission yeast. EMBO rep. 24, e55770 (2023). DOI:10.15252/embr.202255770.
Fujita, I., Shitamukai, A., Kusumoto, F., Mase, S., Suetsugu, T., Omori, A., Kato, K., Abe, T., Shioi, G., Konno, D., and Matsuzaki, F. Endfoot regeneration restricts radial glial state and prevents translocation into the outer subventricular zone in early mammalian brain development. Nat. Cell Biol. 22, 26–37 (2020). DOI:10.1038/s41556-019-0436-9. (Figshare)
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Kono, K., Yoshiura, S., Fujita, I., Okada, Y., Shitamukai, A., Shibata, T., and Matsuzaki, F. Reconstruction of Par-dependent polarity in apolar cells reveals a dynamic process of cortical polarization. eLife 8, e45559 (2019). DOI:10.7554/eLife.45559.
Tsunekawa, Y., Terhune, R. K., Fujita, I., Shitamukai, A., Suetsugu T., and Matsuzaki. F. Developing a de novo targeted knock-in method based on in utero electroporation into the mammalian brain. Development 143, 3216–3222 (2016). DOI:10.1242/dev.136325.
Fujita, I., Yamashita, A. and Yamamoto, M. Dynactin and Num1 cooperate to establish the cortical anchoring of cytoplasmic dynein in S. pombe. J. Cell Sci. 128, 1555–1567 (2015). DOI:10.1242/jcs.163840.
Fujita, I., Tanaka, M. and Kanoh, J. Identification of the functional domains of the telomere protein Rap1 in Schizosaccharomyces pombe. PLOS One 7, e49151 (2012). DOI:10.1371/journal.pone.0049151.
Fujita, I., Nishihara, Y., Tanaka, M., Tsujii, H., Chikashige, Y., Watanabe, Y., Saito, M., Ishikawa, F., Hiraoka, Y. and Kanoh, J. Telomere-nuclear envelope dissociation promoted by Rap1 phosphorylation ensures faithful chromosome segregation. Curr. Biol. 22, 1932–1937 (2012). DOI:10.1016/j.cub.2012.08.019.
Fujita, I., Yamashita, A. and Yamamoto, M. Contribution of dynein light intermediate and intermediate chains to subcellular localization of the dynein-dynactin motor complex in Schizosaccharomyces pombe. Genes Cells 15, 359–372 (2010). DOI:10.1111/j.1365-2443.2010.01386.x.
Review articles
Fujita, I. and Matsuzaki, F. Structural homeostasis of neural stem cells in the development of the mammalian cerebral cortex (in Japanese). Saibou 50 (7), 375–378 (2018).
Summary of research articles
A force balance model for a cell size-dependent meiotic nuclear oscillation in fission yeast
This paper describes a model for the horsetail movement, a microtubule-dependent nuclear oscillation in fission yeast meiosis. We showed that the model considering microtubule pulling and pushing forces recapitulates the robust oscillation.
Endfoot regeneration restricts radial glial state and prevents translocation into the outer subventricular zone in early mammalian brain development
This paper reported a new property of the neural stem cell, raial glia, in the mammalian brain development.
Reconstruction of Par-dependent polarity in apolar cells reveals a dynamic process of cortical polarization